Lead generation of UPPS inhibitors targeting MRSA: Using 3D-QSAR pharmacophore modeling, virtual screening, molecular docking, and molecular dynamic simulations
Undecaprenyl Pyrophosphate Synthase (UPPS) is a vital target enzyme in the early stages of bacterial cell wall biosynthesis. UPPS inhibitors have antibacterial activity against resistant strains such as MRSA a...
Source: Chemistry Central Journal - Category: Chemistry Authors: Basma M. Qandeel, Samar Mowafy, Khaled Abouzid and Nahla A. Farag Tags: Research Source Type: research