Xylitol for the prevention of acute otitis media episodes in children aged 1-5 years: a randomised controlled trial

Conclusions
Regular use of xylitol did not prevent AOM, URTIs or dental caries in a trial with limited statistical power. A post-hoc analysis indicated that URTIs were less common with xylitol exposure during the COVID-19 pandemic, but this finding could be spurious.

Trial registration number
NCT03055091.

Source: Archives of Disease in Childhood - January 22, 2024 Category: Pediatrics Authors: Persaud, N., Azarpazhooh, A., Keown-Stoneman, C., Birken, C. S., Isaranuwatchai, W., Maguire, J. L., Mamdani, M., Allen, C., Mason, D., Kowal, C., Jaleel, M., Bazeghi, F., Thorpe, K. E., Laupacis, A., Parkin, P. C. Tags: Open access Original research Source Type: research