Salivary Th17 cytokine, human β-defensin 1–3, and salivary scavenger and agglutinin levels in Crohn’s disease

ConclusionsCrohn ’s disease does not relate to salivary antimicrobial hBD 1–3 or SALSA levels. While Crohn’s disease patients have higher salivary Th17 cytokine levels in comparison to systemically healthy controls, an independent association between Crohn’s disease and Th17 cytokine profile is still missing .Clinical relevanceDiminished Th17 cytokine response in Crohn ’s disease, which might be related to genetic susceptibility, can be also visualized in saliva.

http://link.springer.com/10.1007/s00784-024-05509-5

Source: Clinical Oral Investigations - January 22, 2024 Category: Dentistry Source Type: research