Immune checkpoint inhibitor-induced isolated adrenocorticotropic hormone deficiency: a systematic review

ConclusionIAD was predominant in elderly male patients mainly receiving anti-PD-1 or anti-PD-L1 antibodies. It was sometimes difficult to recognize IAD at first glance since non-specific symptoms were common and asymptomatic cases of IAD were also reported. Although IAD can be deadly, it usually does not affect the continued use of ICIs.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research