Sleep Disruption Moderates the Daily Dynamics of Affect and Pain in Sickle Cell Disease

Persons with sickle cell disease (SCD) often experience pain that can interfere with quality of life and daily activities. Pain can modulated by affect and sleep continuity; however, few studies have explored how these factors complementarily influence pain in adults with SCD. The study aims were to investigate 1) whether pain levels were heightened on days characterized by low positive affect and high negative affect, and 2) whether the relationship between affect and pain was intensified following nights of disrupted sleep.

Source: The Journal of Pain - January 17, 2024 Category: Materials Science Authors: Jennifer D. Ellis, Shahin Samiei, Sameer Neupane, Caitlin DuPont, Lakeya McGill, Philip Chow, Sophie Lanzkron, Jennifer Haythornthwaite, Claudia M. Campbell, Santosh Kumar, Patrick H. Finan Source Type: research