Higher Cumulative Dose of Opioids and Other Sedatives are Associated with Extubation Failure in Norwood Patients

ConclusionHigher cumulative opioid doses were associated with a greater incidence of extubation failure in infants post-Norwood procedure. Therefore, patients with higher cumulative doses of opioids should be more closely evaluated for extubation readiness in this population. Low end-tidal CO2 and low pulse-to-respiratory quotient were also associated with failed extubation. Consideration of the pulse-to-respiratory quotient in the extubation readiness assessment can be beneficial in the Norwood population.
Source: Pediatric Cardiology - Category: Cardiology Source Type: research