Most UK cardiovascular disease trial protocols feature criteria that exclude ethnic minority participants: systematic review

ObjectivesWe systematically reviewed UK cardiovascular disease (CVD) randomised controlled trial (RCT) protocols to identify the proportion featuring eligibility criteria that may disproportionately exclude ethnic minority (EM) participants.MethodsWe searched MEDLINE, Embase and Cochrane Library databases, January 2014-June 2022, to identify UK CVD RCT protocols. We extracted non-clinical eligibility criteria from trial protocols and inductively categorised the trials by their language, consent and broad (ambiguous) criteria.

Source: Journal of Clinical Epidemiology - January 10, 2024 Category: Epidemiology Authors: Jhulia dos Santos, Shoba Dawson, Carmel Conefrey, Talia Isaacs, Mahwar Khanum, Saba Faisal, Sangeetha Paramasivan Tags: EDI series Source Type: research