Long-Term Voclosporin Treatment Looks Promising for Lupus Nephritis Patients

AURORA 2, a double-blind, phase 3 study, evaluated the long-term safety, tolerability and efficacy of voclosporin compared to placebo in patients with lupus nephritis receiving an additional two years of treatment following completion of the one-year AURORA 1 study. Patients enrolled in AURORA 2 continued to receive the same treatment randomly assigned in AURORA 1, in combination with mycophenolate mofetil and low-dose glucocorticoids. Saxena et al. propose that the rapid renal response achieved with voclosporin treatment has long-term benefits, supported by stable kidney function over the three-year treatment period.
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Biologics/DMARDs Conditions Systemic Lupus Erythematosus Lupus nephritis voclosporin Source Type: research