CK1 δ/ε inhibition induces ULK1-mediated autophagy in tumorigenesis

CONCLUSION: Our results provide evidence for the role of CK1δ/ε in the regulation of tumorigenesis via the ULK1-mediated autophagy, and also suggest the impact of CK1δ/ε inhibition on tumor growth and its significance as a potential therapeutic target.PMID:38185060 | DOI:10.1016/j.tranon.2023.101863

Source: Translational Oncology - January 7, 2024 Category: Cancer & Oncology Authors: Vivian Weiwen Xue Shanshan Liu Qi Sun Jiong Ning Huan Li Weilan Wang Sapna Sayed Xibao Zhao Li Fu Desheng Lu Source Type: research