Analysis of abnormal expression of signaling pathways in PQ-induced acute lung injury in SD rats based on RNA-seq technology

Conclusion: The signaling pathways enriched with these differentially expressed genes are summarized, and the important mechanisms mediated through these pathways in acute lung injury during paraquat poisoning are outlined to identify important targets for AH2QDS treatment of acute lung injury due to paraquat exposure, information that will be used to support a subsequent in-depth study on the mechanism of PQ action.PMID:38175690 | DOI:10.1080/08958378.2023.2300373

Source: Inhalation Toxicology - January 4, 2024 Category: Respiratory Medicine Authors: Nan Li Yue Huang Yang Yi Jin Qian Qi Li Shuang-Qin Xu Hang-Fei Wang Xin-Xin Wu Ji-Chao Peng Li-Hua Li Jin-Jian Yao Xiao-Ran Liu Source Type: research