Methylation of PLK-1 Potentially Drives Bendamustine Resistance in Leukemia Cells

CONCLUSIONS: Our findings indicate that the methylation of the PLK-1 gene plays a pivotal role in modulating PLK-1 expression and is central to the development of bendamustine resistance in leukemia cells.PMID:38072417 | DOI:10.1272/jnms.JNMS.2024_91-206

Source: Journal of Nippon Medical School - December 10, 2023 Category: Universities & Medical Training Authors: Toshikazu Itabashi Takahiro Ueda Ryohei Fukunaga Takeshi Asano Yasuhiko Itoh Source Type: research