Hippo/YAP1 promotes osteoporotic mice bone defect repair via the activating of Wnt signaling pathway

CONCLUSION: This study elucidates the role of Hippo/YAP1 in promoting the repair of osteoporotic bone defects in aged mice. Mechanistically, YAP1 functions by activating the Wnt/β-catenin pathway, and this process is not independent of TEAD1.PMID:38184268 | DOI:10.1016/j.cellsig.2024.111037

Source: Cellular Signalling - January 6, 2024 Category: Cytology Authors: Kehan Li Linan Liu Hanghang Liu Yao Liu Jiawei Xing Jian Song En Luo Source Type: research