Diagnosis of neuroborreliosis in the context of local seroprevalence: A chart review study and a methodological overview

CONCLUSION: Our results suggest that recombinant antigen-based two-tier serology from solely the sera might have sufficient positive predictive value to verify NB in young individuals with characteristic anamnestic data in our region. When parallel serum-CSF testing is warranted, AI should have priority. IgG and albumin concentrations in the both serum and the CSF, the potential time of exposure and the nature and duration of symptoms form the bare minimal set of data for conclusive testing.PMID:38174513 | DOI:10.4103/0972-9062.374040
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Authors: Source Type: research