Levels of cytokines in the cerebrospinal fluid of patients with psychotic disorders compared to individually matched healthy controls

CONCLUSIONS: We found no evidence of increased IL-6 and IL-8 in patients with recent-onset psychotic disorders in contrary to previous findings in meta-analyses of CSF cytokines. Secondary analyses found indication of higher IL-4, decreased IL-16, and borderline increased IFN-γ in patients, neither of which have previously been reported on in CSF analyses of individuals with psychotic disorders.PMID:38160934 | DOI:10.1016/j.bbi.2023.12.035

Source: Brain, Behavior, and Immunity - December 31, 2023 Category: Neurology Authors: Rose Jeppesen Nis Borbye-Lorenzen Rune Haubo Bojesen Christensen Nina Vindegaard S ørensen Ole K öhler-Forsberg Kristin Skogstrand Michael Eriksen Benros Source Type: research