The effectiveness of interventions in reducing pain related to orthodontic separation: a systematic review and meta-analysis

CONCLUSIONS: The application of LLLT decreased the pain induced by the separation during the first day of teeth separation; the pain reduction showed an increase from 6 h to the end of the 24 h. However, the evidence is weak to moderate. The analgesics reduced the pain compared to placebo; this pain reduction had shown an increase from 6 h to the end of the 24 h. The strength of the evidence is moderate. Naproxen gel effectively reduced the pain compared to placebo; the evidence in this regard is moderate. Naproxen gel effectively reduced the pain compared to placebo, but it was less effective than the oral intake of non-steroidal anti-inflammatory drugs. However, the evidence in this regard is moderate.REGISTRATION: This systematic review was registered with PROSPERO (CRD42022335553) during the first stages of its conduction.PMID:38168817 | DOI:10.1093/ejo/cjad078
Source: European Journal of Orthodontics - Category: Dentistry Authors: Source Type: research