Pharmacotherapies for Migraine and Translating Evidence From Bench to Bedside

Migraine is a ubiquitous neurologic disorder that afflicts more than 1 billion people worldwide. Recommended therapeutic strategies include the use of acute and, if needed, preventive medications. During the past 2 decades, tremendous progress has been made in better understanding the molecular mechanisms underlying migraine pathogenesis, which in turn has resulted in the advent of novel medications targeting signaling molecule calcitonin gene –related peptide or its receptor. Here, we provide an update on the rational use of pharmacotherapies for migraine to facilitate more informed clinical decision-making.

Source: Mayo Clinic Proceedings - January 4, 2024 Category: Internal Medicine Authors: Messoud Ashina, Jan Hoffmann, H åkan Ashina, Debbie L. Hay, Yadira Flores-Montanez, Thien Phu Do, Roberto De Icco, David W. Dodick Tags: Review Source Type: research