Refined innate plasma signature after rVSV ΔG-ZEBOV-GP immunization is shared among adult cohorts in Europe and North America

ConclusionEleven additional biomarkers refined the previously found 5-biomarker Geneva signature. The refined signature better discriminated between different doses, was strongly associated with the risk of adverse events and with antibody responses and was validated in a separate cohort.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research