Harnessing the Power of CAR-NK Cells: A Promising Off-the-Shelf Therapeutic Strategy for CD38-Positive Malignancies

CONCLUSION: The in vitro findings indicated that the anti-CD38 CAR-NK cells have the potential to be used as an off-the-shelf therapeutic strategy against CD38-positive malignancies. It is recommended that the present engineered NK cells undergo additional preclinical investigations before they can be considered for subsequent clinical trial studies.PMID:38102941 | DOI:10.22034/iji.2023.100424.2691

Source: Iranian Journal of Immunology - December 16, 2023 Category: Allergy & Immunology Authors: Maryam Asadi Razie Kiani Vahid Razban Seyed Nooreddin Faraji Amirhossein Ahmadi Jafar Fallahi Amin Ramezani Nasrollah Erfani Source Type: research