Thiamin (Vitamin B < sub > 1 < /sub > ) - A scoping review for Nordic Nutrition Recommendations 2023

Food Nutr Res. 2023 Nov 13;67. doi: 10.29219/fnr.v67.10290. eCollection 2023.ABSTRACTOnly a few studies have explored relationships between thiamine intake and function, and a few studies have examined the effects of supplements on various clinical or biochemical outcomes. None of these studies, however, makes a useful contribution to understanding requirements in healthy populations. The requirement of thiamine relates to energy and carbohydrate intake. Clinical signs of deficiency have been observed at intakes below 0.5 mg/day, which corresponds to 0.05 mg/MJ. In other studies, thiamine excretion in the urine and normalisation of enzyme activity were normalised at intakes of 0.07-0.08 mg/MJ. The lower limit of intake thus estimates at 0.05 mg/MJ. It has not been possible to set a safe upper intake level for thiamine due to a lack of data. Studies on pregnant and lactating women indicate a higher requirement as assessed by biochemical parameters. A few studies indicate that thiamine utilisation is impaired among elderly subjects.PMID:38084159 | PMC:PMC10710862 | DOI:10.29219/fnr.v67.10290
Source: Food and Nutrition Research - Category: Nutrition Authors: Source Type: research