Prevalence of differentiated high-grade thyroid carcinoma among well-differentiated tumors: a systematic review and meta-analysis

CONCLUSIONS: Following the current WHO indications, some tumors will be reclassified as DHGTC. The proportion of tumors with high-grade features is relevant in FTC, solid trabecular and histologically aggressive PTC subtypes. A remarkable enrichment in DHGTC among patients with poor prognosis confirms the negative impact of high-grade features on outcome.PMID:38115626 | DOI:10.1089/thy.2023.0350
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Authors: Source Type: research