The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m < sup > 6 < /sup > A-dependent stabilization of AURKA mRNA

In conclusion, the findings of our study suggest that increased YTHDF1 stability induced by PIN1 promotes breast tumorigenesis via the stabilization of AURKA mRNA. Targeting the PIN1/YTHDF1 axis may represent a novel therapeutic strategy for breast cancer.PMID:38147203 | DOI:10.1007/s12272-023-01480-z
Source: Archives of Pharmacal Research - Category: Drugs & Pharmacology Authors: Source Type: research