Brain Structural Abnormalities in a Group of Never-Medicated Patients With Long-Term Schizophrenia.

CONCLUSIONS: The accelerated age-related decline in prefrontal and temporal cortical thickness in never-medicated schizophrenia patients suggests a neuroprogressive process in some brain regions. Slower age-related cortical thinning of the superior parietal cortex and striatal volumetric abnormalities unrelated to age suggest different pathological processes over time in these regions.
PMID: 26085040 [PubMed - as supplied by publisher]

Source: The American Journal of Psychiatry - June 18, 2015 Category: Psychiatry Authors: Zhang W, Deng W, Yao L, Xiao Y, Li F, Liu J, Sweeney JA, Lui S, Gong Q Tags: Am J Psychiatry Source Type: research