Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain

CONCLUSIONS: Our data support the usefulness of in silico approaches for drug repositioning to provide a potential adjunctive therapy for TB.PMID:38126492 | PMC:PMC10740574 | DOI:10.1590/0074-02760230143

Source: Memorias do Instituto Oswaldo Cruz - December 21, 2023 Category: Infectious Diseases Authors: Adri án Rodríguez-Carlos Yolanda Jacobo-Delgado Alan Orlando Santos-Mena Mariana H Garc ía-Hernández Luis Adrian De Jesus-Gonzalez Edgar E Lara-Ramirez Bruno Rivas-Santiago Source Type: research