Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders

Neurochem Res. 2023 Dec 19. doi: 10.1007/s11064-023-04067-8. Online ahead of print.ABSTRACTNeurological disorders are a major group of non-communicable diseases affecting quality of life. Non-Coding RNAs (ncRNAs) have an important role in the etiology of neurological disorders. In studies on the genesis of neurological diseases, aquaporin 4 (AQP4) expression and activity have both been linked to ncRNAs. The upregulation or downregulation of several ncRNAs leads to neurological disorder progression by targeting AQP4. The role of ncRNAs and AQP4 in neurological disorders is discussed in this review.PMID:38114727 | DOI:10.1007/s11064-023-04067-8

Source: Neurochemical Research - December 19, 2023 Category: Neuroscience Authors: Zahra Yaghoobi Shahrzad Sadat Seyed Bagher Nazeri Amir Asadi Ehsan Derafsh Abdolkarim Talebi Taheri Zeinab Tamtaji Ehsan Dadgostar Fatemeh Rahmati-Dehkordi Michael Aschner Hamed Mirzaei Omid Reza Tamtaji Fatemeh Nabavizadeh Source Type: research