Prevalence and clinical implications of germline pathogenic variants in cancer predisposing genes in young patients across sarcoma subtypes

Conclusion
Our findings reveal that a high proportion of young patients with sarcomas presented a GPV in a CPG, underscoring the urgency of establishing appropriate genetic screening strategies for these individuals and their families.

Source: Journal of Medical Genetics - December 21, 2023 Category: Genetics & Stem Cells Authors: Carvalho, N. d. A. d., Santiago, K. M., Maia, J. M. L., Costa, F. D., Formiga, M. N., Soares, D. C. d. Q., Paixao, D., Mello, C. A. L. d., Costa, C. M. L. d., Rocha, J. C. C. d., Rivera, B., Carraro, D. M., Torrezan, G. T. Tags: Open access Cancer genetics Source Type: research