CircZNF609 regulates pulmonary fibrosis via miR-145-5p/KLF4 axis and its translation function

CONCLUSIONS: Our data indicate that circZNF609 is a critical regulator of fibroblast activation and silica-induced lung fibrosis. The circZNF609 and its derived peptides may represent novel promising targets for the treatment of pulmonary fibrosis.PMID:38105235 | PMC:PMC10726587 | DOI:10.1186/s11658-023-00518-w
Source: Cellular and Molecular Biology Letters - Category: Biochemistry Authors: Source Type: research