Troponin I Tyrosine Phosphorylation Beneficially Accelerates Diastolic Function

CONCLUSIONS: We have demonstrated that tyrosine kinase phosphorylation of TnI is a novel mechanism to directly and beneficially accelerate myocardial relaxation in vivo.PMID:38095088 | DOI:10.1161/CIRCRESAHA.123.323132

Source: Circulation Research - December 14, 2023 Category: Cardiology Authors: Lorien G Salyer Hussam E Salhi Elizabeth A Brundage Vikram Shettigar Sarah L Sturgill Helena Zanella Benjamin Templeton Eaman Abay Kathryn M Emmer Jeovanna Lowe Jill A Rafael-Fortney Narasimham Parinandi D Brian Foster Timothy A McKinsey Kathleen C Woulfe Source Type: research