Vitexin along with verapamil downregulates efflux pump P-glycoprotein in macrophages and potentiate M1 to M2 switching via TLR4-NF- κB-TNFR2 pathway in lipopolysaccharide treated mice

In conclusion, combined vitexin and verapamil treatment could be used as a promising therapy to regulate P-gp expression and protection against LPS mediated sepsis and inflammatory damages.PMID:38103391 | DOI:10.1016/j.imbio.2023.152767

Source: Immunobiology - December 16, 2023 Category: Allergy & Immunology Authors: Ayantika Kundu Pratiti Ghosh Biswadev Bishayi Source Type: research