Interaction between intravenous thrombolysis and clinical outcome between slow and fast progressors undergoing mechanical thrombectomy: a post-hoc analysis of the SWIFT-DIRECT trial

Conclusion
In this SWIFT-DIRECT subanalysis, we did not find evidence for a significant interaction of the velocity of infarct growth on the odds of favourable outcome according to treatment by MT alone or combined IVT+MT. However, prior IVT was associated with significantly reduced occurrence of any ICH among slow progressors whereas this was increased in fast progressors.

Source: Journal of NeuroInterventional Surgery - December 19, 2023 Category: Neurosurgery Authors: Marnat, G., Kaesmacher, J., Buetikofer, L., Sibon, I., Saleme, S., Pop, R., Henon, H., Michel, P., Mazighi, M., Kulcsar, Z., Janot, K., Machi, P., Pikula, A., Gentric, J.-C., Hernandez-Perez, M., Krause, L. U., Turc, G., Liebeskind, D. S., Gralla, J., Fis Tags: Ischemic stroke Source Type: research