Microglial APOE4: more is less and less is more

Apolipoprotein E (APOE) is the single greatest genetic risk factor for late onset Alzheimer ’s disease (AD). Yet, the cell-specific effects of APOE on microglia function have remained unclear. Fortunately, two ...

Source: Molecular Neurodegeneration - December 19, 2023 Category: Neurology Authors: Ghazaleh Eskandari-Sedighi and Mathew Blurton-Jones Tags: Editorial Source Type: research