A Randomized, Open-Label, Non-inferiority Clinical Trial Assessing 7 Versus 14  Days of Antimicrobial Therapy for Severe Multidrug-Resistant Gram-Negative Bacterial Infections: The OPTIMISE Trial Protocol

ConclusionThe OPTIMISE trial is the first randomized controlled trial specifically designed to assess the duration of antimicrobial therapy in patients with severe infections by MDR-GNB.Trial RegistrationClinicalTrials.gov, NCT05210387. Registered on 27 January 2022. Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections (OPTIMISE).
Source: Infectious Diseases and Therapy - Category: Infectious Diseases Source Type: research