Evaluating the in vitro developmental toxicity potency of a series of petroleum substance extracts using new approach methodologies (NAMs)

In conclusion, the obtained results support the hypothesis that 3- to 7-ring PACs are the primary inducers of the developmental toxicity induced by some (i.e., poorly refined) petroleum substances and that the observed effect is partially AhR-mediated.PMID:38085275 | DOI:10.1007/s00204-023-03645-7

Source: Archives of Toxicology - December 12, 2023 Category: Toxicology Authors: Jing Fang Ivonne M C M Rietjens Juan-Carlos Carrillo Peter J Boogaard Lenny Kamelia Source Type: research