Porphyromonas gingivalis with collagen immunization induces ACPA-positive rheumatoid arthritis in C3H mice

In conclusion, the C3H mouse model of Pg infection with collagen immunity demonstrated significant alterations in ACPA levels, citrullinated protein expression, and immune cell subpopulations, which could be a crucial factor leading to increased pain, inflammation, and bone destruction.PMID:38065368 | DOI:10.1016/j.clim.2023.109859

Source: Clinical Immunology - December 8, 2023 Category: Allergy & Immunology Authors: Chao Yang Zhixing Hu Lili Wang Luochangting Fang Xiaoxiao Wang Qun Li Liting Xu Jialin Wang Chunfang Liu Na Lin Source Type: research