Genomic characterization of vulvar squamous cell carcinoma reveals differential gene expression based on clinical outcome

CONCLUSIONS: ACVR2A and TGM3 are significantly under-expressed in tumors with poor outcome, suggesting they may play a role in tumor suppression. Clinical outcome of VSCC appears independent of MSI, TMB, or PD-L1 status.PMID:38086165 | DOI:10.1016/j.ygyno.2023.11.026

Source: Gynecologic Oncology - December 12, 2023 Category: Cancer & Oncology Authors: Mary E Gordinier Geoffrey F Schau Shanna B Pollock Lisa B E Shields Sameer Talwalkar Source Type: research