Lung ultrasound –guided fluid resuscitation in neonatal septic shock: A randomized controlled trial

Conclusion: Lung ultrasound is a noninvasive and convenient tool for predicting fluid overload in neonatal septic shock. Fluid resuscitation guided by lung ultrasound can shorten the length of hospital and NICU stays, reduce the amount of fluid used in the first 6  h, and reduce the risk of acute kidney injury and intracranial hemorrhage.Trial registration: Registered in Guangdong Second Provincial General Hospital: 2021-IIT-156-EK, date of registration: November 13, 2021. And ClinicalTrials.gov: NCT06144463 (retrospectively registered).What is Known:• Excessive fluid resuscitation in neonates with septic shock had worse outcomes.What is New:• Lung ultrasound should be routinely used to guide fluid resuscitation in neonatal septic shock.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research