Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders

Major psychiatric disorders such as schizophrenia (SCZ) and bipolar disorder (BPD) are complex genetic mental illnesses. Their non-Mendelian features, such as those observed in monozygotic twins discordant for...

Source: BMC Medicine - December 12, 2023 Category: Internal Medicine Authors: Junping Ye, Zhanwang Huang, Qiyang Li, Zhongwei Li, Yuting Lan, Zhongju Wang, Chaoying Ni, Xiaohui Wu, Tingyun Jiang, Yujing Li, Qiong Yang, Junghwa Lim, Cun-Yan Ren, Meijun Jiang, Shufen Li, Peng Jin & hellip; Tags: Research article Source Type: research