Methylation Signatures as Biomarkers for Non-Invasive Early Detection of Breast Cancer: A Systematic Review of the Literature

Breast cancer is the most common type of cancer in women across the globe with an estimated 287,850 newly diagnosed cases in the United States in 2022 [1]. Breast cancer is a heterogeneous group of pathologic entities with different biologic behaviors and includes various subtypes such as hormone-receptor-positive, triple negative, and Human Epidermal Receptor (HER) 2/neu-positive breast cancers. All of these subtypes have distinct progression mechanisms, which require different management approaches [2].

Source: Cancer Genetics and Cytogenetics - December 11, 2023 Category: Genetics & Stem Cells Authors: Tessa Gonzalez, Qian Nie, Lubna N. Chaudhary, Donald Basel, Honey V. Reddi Source Type: research