EBRT reduces risk of subsequent mastectomy in patients with invasive breast cancer
(American Society for Radiation Oncology) Standard external beam radiation therapy (EBRT) provided a higher breast preservation rate than brachytherapy in women age 66 and older with invasive breast cancer, according to a study published in the Feb. 1, 2014, print edition of the International Journal of Radiation Oncology*Biology*Physics, the official scientific journal of the American Society for Radiation Oncology.
Conclusion: Our results support the hypothesis that CAV-1 knockdown by siRNA causes increased radiosensitivity in basal-like TNBC cells. The mechanisms associated with this effect are reduced DNA repair through delayed CAV-1-associated EGFR nuclear accumulation and induction ofG2/M arrest and apoptosis through the combined effects of CAV-1 siRNA and radiation.Cell Physiol Biochem 2017;44:778 –791
Artificial intelligence occupies powerful space in the medical industry. Today, many clinics and hospitals have tablets in place of receptionists, deep learning models are alreadydiagnosing TB, and Massachusetts Institute of Technology researchers are usingalgorithms to detect breast cancer before a breast imager can. These advancements accelerate image interpretation, and in a lot of ways, make a radiologist or technologist’s job easier; however, is technology poised to obliterate the radiologist’s role altogether? According to the financial management firmCornerstone Capital Group, out of the 16 million ...
Conclusion These findings provide experimental support for the use of curcumin as a modulator of tumor cell pharmacointeraction in cannabinoid based therapies. To achieve synergism dose ratios should be established for each cell type and ratiometric dosing be considered. Graphical abstract
Conclusion The study of the SN together with the technique of the SLN allows a more precise staging of the axillary involvement, in patients with breast cancer, than just the SLN technique.
In conclusion, axillary treatment can be avoided in patients without metastatic involvement or micrometastases in the sentinel lymph node. However, there is no evidence to make a recommendation of axillary treatment in N1 patients, so individualized analysis of patient risk factors is needed.
Conclusion Our results indicate that distinct trajectory groups can be used as a screening tool to identify patients who may be at an increased risk of psychological distress over time. Screening for psychological distress from at disease diagnosis is important and necessary to identify patients who are at an increased risk of elevated distress or at risk of experiencing psychological distress over time.
This study is the first to link a specific SNP/gene cluster to AIA risk independent of candidate gene bias. Aromatase inhibitor‐related arthralgias (AIA) are common and may lead to therapy noncompliance. Whereas traditional gene studies to identify arthralgia risk have been limited in scope, we employed a novel analytic algorithm to link a specific SNP/gene cluster to AIA risk independent of candidate gene bias.
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Conclusion: both CXCR7 and NF-ĸB are related to the malignant grade of the breast cancer and lymphatic metastasis, which may be regarded as in important indicator to judge the prognosis of the breast cancer and be expected to be the new target of curing part of the breast cancer.
Nothing has captured the march of wealth and progress like any society’s ability to light up the night—first with campfires and torches, then with gas lamps, finally with incandescent lights. Franklin Roosevelt’s 1936 Rural Electrification Act was an effort both to bring modernity to the 90% of American farms that lacked electricity and to help jolt the American economy, which was still deep in the Depression. The modern nighttime image of the Korean peninsula as seen from space, with darkness north of the 38th parallel and brilliant light in the vibrant south, powerfully captures the connection between c...