Prevalent landscape of tumor genomic alterations of luminal B1 breast cancers using a comprehensive genomic profiling assay in Taiwan

CONCLUSIONS: PIK3CA, FGFR1, and BRCA1/2 were the most prevalent actionable alterations among Taiwanese luminal B1 breast cancer. Moreover, PTEN and BRCA1/2 was significantly associated with disease relapse.PMID:38070067 | DOI:10.1007/s12282-023-01524-8

Source: Breast Cancer - December 9, 2023 Category: Cancer & Oncology Authors: Bo-Fang Chen Yi-Fang Tsai Pei-Ju Lien Yen-Shu Lin Chin-Jung Feng Yen-Jen Chen Han-Fang Cheng Chun-Yu Liu Ta-Chung Chao Jiun-I Lai Ling-Ming Tseng Chi-Cheng Huang Source Type: research