Epidermal growth factor receptor inhibition by anti‐CD147 therapy in cutaneous squamous cell carcinoma
ConclusionInhibition and downregulation of CD147 in cutaneous SCC resulted in suppression of the malignant phenotype in vitro and in vivo, which may be mediated in part by an alteration in EGFR expression. As a result, CD147 may serve as a potential therapeutic target for advanced cutaneous SCC. © 2014 Wiley Periodicals, Inc. Head Neck, 2015
Source: Head and Neck - Category: ENT & OMF Authors: John W. Frederick, Larissa Sweeny, Yolanda Hartman, Tong Zhou, Eben L. Rosenthal Tags: Original Article Source Type: research
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