Relationship between plasma NFL and disease progression in Parkinson ’s disease: a prospective cohort study

ConclusionsPlasma NFL exhibits a tendency to increase with disease progression, and elevated baseline plasma NFL can serve as a predictor for accelerated motor deterioration and cognitive decline in PD. However, plasma NFL does not have high accuracy to distinguish individuals with early-stage PD from HC.
Source: Journal of Neurology - Category: Neurology Source Type: research