Phenytoin is associated with increased risk of osteoporosis and fragility fractures in adult epileptic patients

ConclusionEpileptic patients on phenytoin therapy that were 18 –55 years old exhibited higher associated risk of osteoporosis and osteoporotic-fragility fractures of various regions. Patients that undergo phenytoin therapy for epilepsy treatment should be educated on the increased risk of bone fractures and have appropriate lifestyle and diet modifications.
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research