Detour of bile acid routes as therapeutic roadmap for cholemic nephropathy

Acute kidney injury (AKI) is frequent in hospitalized patients with chronic liver disease (i.e. up to 50% in some studies) and is associated with high morbidity and mortality.1 –3 Causes of AKI in patients with liver disease are numerous and differential diagnosis remains a clinical conundrum in 2023.4,5 This is based on (i) the frequently observed overlap of several initiating factors and diseases and (ii) the lack of non-invasive clinical tests showing high sensitivity and specificity to discriminate different entities of AKI in patients with liver disease.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Editorial Source Type: research