Tumor grade and molecular characteristics associated with survival in sporadic medullary thyroid carcinoma

CONCLUSIONS: IMTCGS grading was associated with DSS independently of other clinical, pathological, and molecular factors. Moreover, MTC grading was associated with RET and RAS patterns, which explains, at least in part, the molecular basis of the aggressive behavior of high-grade MTC.PMID:38047536 | DOI:10.1089/thy.2023.0482

Source: Thyroid : official journal of the American Thyroid Association - December 4, 2023 Category: Endocrinology Authors: Simona Censi Francesca Galuppini Cristina Clausi Fiammetta Battheu Jacopo Manso Ilaria Piva Sara Corvaglia Maria Chiara Pedron Alberto Mondin Maurizio Iacobone Francesca Torresan Isabella Merante Boschin Loris Bertazza Susi Barollo Gianmaria Pennelli Cate Source Type: research