Con: Mechanical Ventilation during Cardiopulmonary Bypass

The ventilatory strategy to adopt during cardiopulmonary bypass (CPB) is still debated. The rationale for using CPAP or low-tidal volume mechanical ventilation would be to counteracting alveolar collapse and improve ischemia phenomena and passive alveolar diffusion of oxygen. Although there are several studies supporting the hypothesis of a positive effect on oxygenation and systemic inflammatory response, a real clinical impact of ventilation during CPB is controversial. Furthermore, the biases present in literature make the studies results non-unique in their interpretation.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Pro and Con Source Type: research