Blood Biomarkers Discriminate Cerebral Amyloid Status and Cognitive Diagnosis when Collected with ACD-A Anticoagulant

CONCLUSION: Our results suggest that the Aβ42/40 ratio is useful in discriminating clinician-rated elevated cerebral amyloid status and that NFL is useful for discriminating cognitive impairment status. These findings reinforce the growing body of evidence regarding the general utility of these biomarkers and extend their utility to plasma collected in a non-traditional anticoagulant.PMID:38047367 | DOI:10.2174/0115672050271523231111192725

Source: Current Alzheimer Research - December 4, 2023 Category: Neurology Authors: Zachary Green Paul Kueck Casey John Jeffrey Burns Jill Morris Source Type: research