Troponin T in spinal and bulbar muscular atrophy (SBMA)
Serum biomarkers that might detect clinical progression are currently lacking for Spinal and bulbar muscular atrophy (SBMA), thus limiting the effectiveness of possible future pharmacological trials. Elevation of cardiac troponin T (cTnT) unrelated to myocardial damage in a motor neuron (MN) disease as amyotrophic lateral sclerosis (ALS) was associated to disease severity.We enrolled 47 SBMA patients and 5 Spinal muscular atrophy (SMA) type 3 adult patients as control group; each SBMA patient was evaluated at baseline and at one-year follow-up visit.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Musso Giulia, Blasi Lorenzo, Mion Monica Maria, Fortuna Andrea, Sabbatini Daniele, Zaninotto Martina, Bello Luca, Pegoraro Elena, Basso Daniela, Plebani Mario, Sorar รน Gianni Tags: Clinical short communication Source Type: research