Persistent pain and its predictors after starting anti-tumour necrosis factor therapy in psoriatic arthritis: what is the role of inflammation control?

CONCLUSIONS: A substantial proportion of PsA patients reported unacceptable pain throughout the first anti-TNF treatment year. At 12 months, refractory pain constituted about two-thirds of this remaining pain load. More objective signs of inflammation at anti-TNF initiation were associated with less future refractory pain. This highlights insufficient effect of biologics in patients with inflammation-independent pain, warranting alternative treatments.PMID:38031733 | DOI:10.1080/03009742.2023.2258644

Source: Scandinavian Journal of Rheumatology - November 30, 2023 Category: Rheumatology Authors: C Roseman J K Wallman A J öud Mec Schelin J T Einarsson E Lindqvist J Lampa M C Kapetanovic T Olofsson Source Type: research