Postoperative wound infection by nontuberculous mycobacteria; case series in Dhaka Medical College Hospital of Bangladesh

Key Clinical MessageThe incidence of nontuberculous mycobacterial (NTM) infections after operations is increasing in Bangladesh but data regarding clinical presentation, diagnosis, treatment, and prognosis after treatment are lacking. In this case series, three patients having persistent serous discharge from incision wound after operation were studied. Discharge from wounds were collected, wet film microscopy was performed for pus cells and fungus, Gram stain, Ziehl-Neelsen (ZN) stain, culture in routine culture media and Lowenstein-Jensen (LJ) media, Xene-Xpert for mycobacterium tuberculosis (MTB), polymerase chain reaction (PCR) for NTM were done. NTM-positive patients were treated initially for 6  weeks with four drugs regimen (clarithromycin 500 mg 12 hourly, ciprofloxacin 500 mg 12 hourly, linezolid 400 mg 12 hourly, and amikacin 500 mg 12 hourly), followed by 5 months with three drugs regimen (clarithromycin 500 mg 12 hourly, ciprofloxacin 500 mg 12 hourly, and linezolid 400 mg 12 hourly) as a maintenance dose. Cessation of discharge occurred within 3–4 weeks after starting treatment, and the wounds were healed.

Source: Clinical Case Reports - November 28, 2023 Category: General Medicine Authors: Kakali Halder, Nusrat Noor Tanni, Rubaiya Binte Kabir, Maherun Nesa, Md. Faizur Rahman, Rizwana Zaman, Farjana Binte Habib, Noor ‐E‐Jannat Tania, Md. Asaduzzaman, Azmeri Haque, Akteruzzaman Chowdhury, Avizit Sarker, Nadira Akter, Mahbuba Tags: CASE SERIES Source Type: research