Detour of bile acids routes as therapeutic roadmap for cholemic nephropathy

Acute kidney injury (AKI) is frequent in hospitalized patients with chronic liver disease (i.e. up to 50% in some studies) and associated with high morbidity and mortality 1,2,3. Causes of AKI in liver patients are numerous and differential diagnosis remains a clinical conundrum in 2023 4,5. This is founded in (i) the frequently observed overlap of several initiating factors and diseases and (ii) the lack of non-invasive clinical tests showing high sensitivity and specificity to discriminate different entities of AKI in liver patients 4,5.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Editorial Source Type: research